the early work

Years ago, when I started looking for my first job, wise advisers urged, "Barbara, be enthusiastic! Enthusiasm will take you further than any amount of experience."

How right they were. Enthusiastic people can turn a boring drive into an adventure, extra work into opportunity and strangers into friends.

"Nothing great was ever achieved without enthusiasm," wrote Ralph Waldo Emerson. It is the paste that helps you hang in there when the going gets tough. It is the inner voice that whispers, "I can do it!" when others shout, "No, you can't."

It took years and years for the early work of Barbara McClintock, a geneticist who won the 1983 Nobel Prize in medicine, to be generally accepted. Yet she didn't let up on her experiments. Work was such a deep pleasure for her that she never thought of stopping.